Cell Migration: Catapulting Neurons from the Ventricular Zone?
نویسنده
چکیده
In the developing vertebrate brain, newly born neurons migrate away from the proliferative zones. A new paper suggests that the initial phase of this migration may be propelled by the mechanical properties of the new neurons' processes rather than more conventional mechanisms of cell migration.
منابع مشابه
Involvement of filamin A and filamin A-interacting protein (FILIP) in controlling the start and cell shape of radially migrating cortical neurons.
Precisely regulated radial cell migration out of the ventricular zone is essential for corticogenesis. However, molecular mechanisms controlling the start of migration and the dynamics of migrating cell shape remain elusive. Here, we show novel mechanisms that can tether ventricular zone cells and control migrating cell shape. The novel protein Filamin A-interacting protein (FILIP) interacts wi...
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عنوان ژورنال:
- Current Biology
دوره 17 شماره
صفحات -
تاریخ انتشار 2007